What to Know Before Starting Accutane

Whether you’re nervous or already planning to start, here’s what to know about Accutane, from what to expect to the best ways to handle dry lips and skin.

This article shares personal experiences, not medical advice. Always follow your dermatologist’s instructions.


Accutane, Accutane, Accutane. It’s probably one of the most talked-about medications among teenage girls, and also one of the most misunderstood.

So what exactly is Accutane? It’s a prescription medication called isotretinoin that’s used to treat severe acne, especially when other treatments haven’t worked. It works by reducing oil production in your skin, which helps clear up acne.

Accutane is basically the last resort for bad acne. I tried everything before getting to that point: regular and prescription creams, cutting out dairy and chocolate (which worked for 12 glorious weeks, and then my acne came right back!), and regular medication like doxycycline, an antibiotic used to treat acne. I always say I have the most expensive face in my house.

Honestly, if I hadn’t been so scared to take Accutane, I probably would have saved myself a lot of time, stress, and money. And people are scared because they don’t know what to expect.

So here’s the 411 from the teens I polled.

What to Know Before Starting Accutane

1. If you’re younger than 10th or 11th grade, it may not work to its fullest.
This might not be a medical fact, but in our experience, acne is more likely to come back if you take Accutane when you’re younger. Ask your dermatologist whether now is the right time.

2. Don’t expect to get Accutane at your first appointment.
I had to go through creams and medication first, plus testing, before I actually started.

3. Don’t let the side effects list scare you off.
They’ll give you a long list of possible side effects, and some of them sound really scary. In our experience, most people mainly deal with dryness, and the serious side effects are much less common. But they’re on the list for a reason, so take them seriously. Tell your doctor and your parents right away if you notice changes in your mood, bad headaches, blurry vision, or stomach pain. That’s what the monthly checkups are for, so be honest at every appointment.

4. It’s best to do Accutane in the winter.
Your skin and scalp are very sensitive to the sun, so you need to be extra careful about sun exposure.

5. The biggest effect of Accutane is dryness.
Your skin and lips can get really dry. It’s not just a possible side effect. For many people, it’s the main effect you notice.

6. Get a pill case.
Trust me, it’s hard to remember if you took your pill or not. I filled up my case at the beginning of the week and knew exactly where I was up to.

How to Deal With Accutane Dryness

1. Moisturizer / Face Wash
Keep it simple. Use a basic moisturizer like CeraVe or Neutrogena.

2. Lip Care
The biggest problem is dry lips on Accutane. While you can simply use Aquaphor or Vaseline, really, the best lip care on Accutane is nipple cream like this one (we first shared this dry lips hack in this post). Lansinoh’s lip balm will also work, but it’s a drop runnier so doesn’t stay put as well. It’s a good option if you don’t want to have to repackage your cream! Whatever you use, buy a lot and keep one wherever you go. Near your bed, in the car, in the kitchen, in your backpack… trust me, you’ll want it everywhere.

Ask your LOR what to do on Shabbos about your lips. Sometimes olive oil is an option, but ask what is permissible. 

3. Sunscreen
You MUST wear sunscreen. Your skin is more sensitive while you’re on Accutane, so you can get burned easily, even in the winter.

4. Body
Everybody gets different types of dryness, but if your skin starts feeling tight, try an Aquaphor spray.

5. Hands
Your hands are very likely to get painfully dry, too. Use a moisturizer or hand cream regularly. Wearing white cotton gloves when you sleep can also help.

______

Accutane FAQs

How long does Accutane dryness last?
Dryness usually starts within the first couple of weeks, often with your lips, and lasts for the whole course of treatment, which is usually around four to six months. The good news is that it goes away. Most people find their skin and lips are back to normal within a few weeks of finishing.

Does acne get worse before it gets better on Accutane?
It can. Some people have a flare-up during the first month or so before their skin starts clearing, but not everyone does. If your breakouts get really bad or painful, let your dermatologist know.

Can you wear makeup on Accutane?
Yes. Since your skin will be drier than usual, start with a good moisturizer and choose hydrating makeup, like a dewy foundation or tinted moisturizer, instead of anything too matte or powdery. Remove it gently at night and skip harsh scrubs.

Can you wax or get facials on Accutane?
No. Your skin is much more fragile on Accutane, so waxing, laser hair removal, and strong facial treatments can damage it or cause scarring. Dermatologists usually say to avoid them during treatment and for about six months after. Ask your dermatologist when it’s safe to start again.

Have you tried Accutane? What was your experience? Please share additional information in the comments!

A Note About Accutane: This article shares personal experiences and tips from teens who have taken Accutane. Everyone’s experience is different, and what worked for one person may not work for you. Accutane is a prescription medication that can have side effects, so always follow your dermatologist’s instructions and speak to them about any concerns or questions. This article is for informational purposes only and is not a substitute for medical advice.

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Libby Spero

Libby is a 12th grader who enjoys researching, learning, and sharing great discoveries with other teens.

32 responses to “What to Know Before Starting Accutane”

  1. BR Avatar
    BR

    I had acne as a teen but it got really bad in my low 20s. I was once in a store and a lady I don’t know came over to me and asked me why I don’t consider accutane. I don’t know who she is and really wish to thank her but I was at the dermatologist the next day and startwd accutane the next month. (I was still single then) The best decision in my life. It’s been 10 years and have not seen a pimple since (even during pregnancy). You’ll feel human again – go for it!

  2. C Avatar
    C

    One of my sons did accutane, and he had TERRIBLE side effects. Besides for what’s listed here, he had bone aches that were so bad that he couldn’t sleep, terribly dry eyes (our optometrist said that a lot of ppl damage the oil glands in their eyes with accutane), suicidal thoughts (mild ideation), and a HUGE host of other things. It sounds like his experience was worse than most, but this was his experience.

    People should know that it’s incredibly difficult to do – you have to see the doctor every month before getting your prescription, do bloodwork semi-regularly, and girls need to take monthly pregnancy tests.

    I found it INCREDIBLY difficult to manage while my son was in yeshiva out of town. Ultimately, he had to go off before he completed his treatment, and he still has some acne scarring 🙁

  3. Rina Avatar
    Rina

    I did accutane in high school and it was the best thing! I found aquafor to be the only thing that worked for my lips and hands. it’s almost 10 years later and bh my skin is still pretty clear!
    my doctor required that I take blood tests every month so if you’re bothered by needles it might not be for you
    I do know a few people who had to do 2 courses of accutane for their skin to clear completely

  4. A.N. Avatar
    A.N.

    Anyone knows what its like to start accutane as a newlywed?

    1. SB Avatar
      SB

      FYI- accutane is NOT NOT NOT safe for during a pregnancy!!

    2. C Avatar
      C

      I did accutane in my 20s I was married and had 2 kids. My acne was so bad I got a heter to take birth control for a year (6 months while doing treatment and 6 months after). If you’re married there is a way to do it. Ask your dermatologist and your rav. It was the best thing I ever did for myself. It’s about 12 years later and I still have clear skin. Just a note cerave cream( it comes in a tub) works better than cerave lotion.

      1. Chanie Markowitz Avatar
        Chanie Markowitz

        I did Accutane and my doctor said that you have to be on birth control for only 1 month after you finish the treatment.

  5. PW Avatar
    PW

    Accutane worked really well for me, bH. I did it when I was 19 – started the Sukkos after I came home from seminary. Since one of the side effects is depression, my parents didn’t want me on it during the teenage years, which are turbulent enough without adding this in! I had to do it for 10 months. My dermatologist took monthly blood tests and mailed the pills a few days later always.

  6. BD Avatar
    BD

    I never had to take tests, I just had to confirm I wouldn’t get pregnant that month. there’s a website now, that you fill out the questions when you come home from the dermatologist and your prescription gets filled automatically. no side effects except dryness and I’m delighted 5 years later

  7. K Avatar
    K

    I did accutane right after seminary and it worked really well, even 10 plus years and multiple pregnancies later. However, when I learned about it in pharmacology class in college, after I was finished taking it, the list of side effects are so big and severe and a real possibility, that my professor made a comment that he doesn’t know how it ever got approved. So please be cautious!

  8. Rachel Avatar
    Rachel

    I had to do it twice a few years apart, I used Elizabeth Arden lip cream for my dry lips. It’s expensive but the best!!! Not sure if it’s still available as it was a while ago.

  9. N Avatar
    N

    I had terrible acne as a teenager, and when I was on Accutane, what helped most for dry lips was Carmex medicated lip balm. It’s thicker than all other lip balms. Use sparingly, as it’s medicated…
    https://link.amazon/B082NLIXw

  10. S Avatar
    S

    I did Accutane and it was very effective!
    One of my most difficult side effects were dry eyes. I stopped wearing lenses, and slept with a humidifier and eye cream which is stronger than eye drops. I also found that screens would give me headaches so I set them all to night mode.

  11. CP Avatar
    CP

    I’d love to hear if anyone in their 30’s did it and how it was. I have acne since I’m a teen but was always afraid to take such strong antibiotics. Mostly on my t-zone and it’s hormonal but nothing helps it clear up properly until the next round of pimples arrive. Wondering if I should just consider doing it now or I missed the boat.

    1. ER Avatar
      ER

      I’m in my 30s and recently did Accutane, so you definitely haven’t missed the boat! My acne wasn’t severe, but I had been struggling since i was 19 with constant breakouts, mostly on my chin and occasionally on my cheeks. I tried so many different creams, but nothing really helped, and all they seemed to do was dry out my skin. I finally decided to give Accutane a try, and honestly, I wish I had done it sooner! My skin has cleared up so much, and I haven’t worn face makeup in the longest time. The confidence it’s given me is incredible, and my skin looks and feels amazing. The only side effect I experienced while on it was dry lips and random dryness on my hands at times. Of course, everyone’s experience is different, but for me, it was absolutely life changing and would highly recommend looking into it and discussing it with your dermatologist.

  12. Sarala Avatar
    Sarala

    I’m an eleventh grader and I just finished Accutane about a month ago. It did make my acne way better than what it was though it didn’t work as well as I thought it would. Bh my side effects weren’t so bad so I would be willing to maybe do it again. But it still was not fun. I just want to say thank u to bcp because that’s where I learned to use nipple cream on my lips and it was the. Only. Thing. That. Worked. I owned a bunch at a time and carried it around wherever I went

  13. Sara Avatar
    Sara

    I took accutane in 12th grade and had many of the effects mentioned here- dry lips which never really fully cured, got sunburned for the first and last time in my left, depressive and suidical thoughts. It helped but not enough, and years later I found out about hidradenitis suppurativa, which is why I’m commenting here. It is misdiagnosed for acne many times and especially for those who commented on acne for many years, it is something to look into. Sadly I was only diagnosed 10 years after it started and most of my scars could have been prevented if I had known about it before.

  14. Esther Avatar
    Esther

    My daughter did accutaine in 12th grade and she’s left with very dry eyes 3 years later. Can’t wear contacts for more than 2 hours at a time. Also gets recurring styes. It can damage the meibomian glands in the eye. It’s been a trade off for acne free skin.

  15. gitty Avatar
    gitty

    i did accutane when i was 14 and the results did not last. wish i wouldve waited till i was older
    also, the dry lips did not go away. its not as bad as while on it, but 15 years later and my lips are still dry
    other than dryness, i had no other side effects

  16. Mimi Avatar
    Mimi

    I did it in seminary and was the best decision I made – I am almost 10 years later and don’t get pimples ever bh!
    There is a lip balm in Israel called flexitol that worked amazing for me.
    Also, I became very prone to nosebleeds while I was on it, because of the dryness.

  17. Mom Avatar
    Mom

    I did accutane after seminary and 5 years later it came back. Just fyi if you have the acne gene your acne WILL come back even if you do accutane. I noticed that most people with good results are the girls who took it in highschool which means it was probably teenage acne that would have cleared by itself. If you have acne because of PCOS or you have the acne gene or both like I do Accutane will only help short term. I reccommend Rebecca Meyers the acne coach if anyone is intrested in really understanding their acne and getting long term results. Rebecca explains the science behind your acne and how to keep your skin clear.

    1. TK Avatar
      TK

      I had terrible, terrible acne because of PCOS and tried everything (facials/creams/etc.) and nothing worked. Birth control helped subside it but only temporarily. Accutane cleared me up and I’m still clear!! I did not suffer from dry lips/eyes/skin BH.

      Random note – I got slight acne from taking a prenatal vitamin that contained IODINE – it is known to actually cause acne.

  18. LM Avatar
    LM

    My only regret with Accutane was not taking it sooner. I spent 3 years of highschool always insecure and worried about my face, never leaving the house without makeup and dreading shabbos when my makeup wore off. When I finally took it in 12th grade, after all the symptoms passed (I was taking a very high dose and had constant dry skin, dry nose, dry eyes, dry lips…), I felt so much better about myself. I have PCOS, but 6 years later and it’s still never come back, except for a stray pimple here or there during hormonal seasons. I still have acne scarring from before taking accutane and wish I had known about it/been brave enough to do it sooner.

  19. TSK Avatar
    TSK

    Would anyone recommend Accutane for someone with not such heavy acne?

    1. ER Avatar
      ER

      Yes my acne wasn’t severe (mainly mild-moderate on chin) and I did it! Results are crystal clear BH

    2. Devora Avatar
      Devora

      Yes! I had it mildly on my face but enough that it bothered me . I also had on my back and chest which never cleared from my teen years. I did a course of accurate when I was 35 and my only regret is that I didn’t do it sooner. My skin is clear even after a pregnancy , the only side effects I had were dryness and occasional redness (flushing) which cleared when I stopped.

  20. nc Avatar
    nc

    Ltoeles – I did accutane as a teen and was diagnosed with chrons disease a few years later from it. I had zero symptoms then but testing confirmed this. DO YOUR RESEARCH!! those side affects arent hatched out of nowhere

    1. Fraidy Avatar
      Fraidy

      I was all signed up with my dermatologist to take accutane and then someone told me that their two brothers in law who did it both got Crohn’s. This is not something I would do if you have mild acne.

  21. Esther Avatar
    Esther

    Medicine is incredibly helpful, but I wish more people were aware of the connection between diet and acne. While acne can have several causes, including hormones and genetics, what we eat also plays a SIGNIFICANT role in our skin health (you can research it).

    There are many personal stories of teenagers who have seen improvements in their acne simply by making healthier food choices, such as reducing sugar, white flour, and highly processed foods.

    I think it’s important to raise awareness that dietary changes can be a helpful, natural approach to managing acne, potentially reducing the need for medication and its possible side effects.

    1. EI Avatar
      EI

      I had terrible face acne as a teenager, tried facials and every cream and medication available.
      I also tried cutting out white flour, processed sugar, and dairy for several months.
      NOTHING HELPED, not even slightly.
      I took accutane in seminary. I got very dry lips, dry skin, and dry eyes. None of these ever went away completely 🙁 Just good to be aware of that. I also had depressive moods for the duration of the treatment.
      Either way, it didn’t work completely. My acne came back after seminary, but not as severely.
      As an adult, I still have acne and it’s clearly hormonal and fluctuates with the time of the month. Unfortunately, it you don’t want to start messing with your hormones, there is nothing to do about it.

  22. Sarah Avatar
    Sarah

    I had severe acne and took accutane in high school and my face cleared up beautifully. The side effects were nose bleeds and dry lips. A few months prior to finishing, the monthly blood test showed an increase in my liver enzymes and my dermatologist made me stop taking it immediately. Bh my skin remained clear afterwards but its important to be on top of blood test results when taking it. Good luck!

  23. Yitty Avatar
    Yitty

    Do your research! When my sister was considering it my mom called our family dr for advice and he said he would NOT let his daughter take it.

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